B Pharma Pharmacy 1st Semester Syllabus
Syllabus
FIRST SEMESTER
RPH-101
PHARMACEUTICAL CHEMISTRY-I
(PHARMACEUTICAL INORGANIC CHEMISTRY)
An outline of methods of preparation, tests of identification and special tests (if any), of the individually
mentioned inorganic pharmaceuticals.
Unit I
Sources of impurities and their control.
Limit tests for iron, arsenic, lead, heavy metals, chloride and sulphate.
Pharmaceutically acceptable glass.
Gases and vapors: Inhalants (Oxygen), anesthetics (Nitrous oxide).
Unit II
Topical agents: Protectives (Calamine, Kaolin). Astringents (Zinc sulphate, Alums). Anti-infectives
(Boric acid, Hydrogen peroxide, Povidone-Iodine, Silver nitrate).
Dental products: Dentifrices (Dicalcium Phosphate), anti-caries agents (Sodium fluoride).
Antioxidants : Sodium metabisulphite.
Unit III
Gastrointestinal agents: Antacids (Aluminium hydroxide, Calcium carbonate, Magnesium hydroxide,
Magnesium carbonate-light and heavy, Bismuth sub-carbonate), Combination antacids. Cathartics
(Disodium hydrogen phosphate, Magnesium sulphate). Protective and Adsorbents (Activated charcoal,
Aluminium sulphate).
Miscellaneous agents: Expectorants (Ammonium chloride, Potassium iodide). Respiratory stimulants
(Ammonium hydroxide).
Unit IV
Major intra and extracellular electrolytes: Physiological ions, electrolytes used for replacement
therapy (Sodium chloride, Potassium chloride, Calcium gluconate, Magnesium chloride), Combination
therapy including ORS.
Essential and trace elements: Iron and haematinics (Ferrous sulphate, Ferrous gluconate, Ferric
ammonium citrate). Mineral supplements (Cu, Zn, Cr, Mn, I).
Unit V
Inorganic radiopharmaceuticals: Radioactivity, units of radioactivity and radiation dosimetry,
measurement of radioactivity, hazards and precautions in handling of radiopharmaceuticals, clinical
applications of radiopharmaceuticals.
Co-ordination compounds and complexation: Co-ordination theory, chelates and their pharmaceutical
importance, poison antidotes (Sodium thiosulphate).
RPH-101P
PHARMACEUTICAL CHEMISTRY-I
(PHARMACEUTICAL INORGANIC CHEMISTRY)
PRACTICAL
1. To perform limit test of chloride, sulphate, iron and heavy metal arsenic in the given sample.
Identification tests for acidic and basic radicals.
2. Preparation of following compoundsBoric acid
Magnesium sulphate
Magnesium carbonate
Calcium carbonate
Alum
Zinc sulphate.
BOOKS RECOMMENDED:
1. Pharmacopoeia of India, 1996 Edition, The Controller of Publications, Delhi.
2. Block J.H., Roche E., Soine, T. and Wilson, C., Inorganic, Medicinal & Pharmaceutical Chemistry,
Lea & Febiger, Philadelphia.
3. Atherden L.M., Bentley and Driver’s Text Book of Pharmaceutical Chemistry, Oxford University
Press, London.
4. Miessler, G.L. and Tarr, D.A. Inorganic Chemistry, Dorling Kindersley (India) Pvt. Ltd. (Pearson
Education), New Delhi.
5. Svehla, G. and Sivasankar, B. Vogel's Qualitative Inorganic Analysis, Dorling Kindersley (India)
Pvt. Ltd. (Pearson Education), New Delhi.
6. Rao K.S. and Suresh, C.V. Pharmaceutical Inorganic Chemistry, PharmaMed Press, Hyderabad.
7. Chenchu Lakshmi, N.V. Pharmaceutical Inorganic Chemistry: Theory and Practice, Dorling
Kindersley (India) Pvt. Ltd. (Pearson Education), New Delhi.
RPH-102/RPH-202
PHARMACEUTICS-I
(GENERAL PHARMACY)
Unit I
History of pharmacy and Pharmacopoeia: Origin and development of pharmacy, scope of pharmacy,
introduction to Pharmacopoeias- IP, BP, USP and International Pharmacopoeia. Introduction to
National Formularies and Extra Pharmacopoeia. An introduction to the contents of IP and parts of a
monograph.
Unit II
Prescription: Definition, types of prescription, handling of prescription, legality of prescription and
specific Latin terms used in modern day prescription (sos, od, bd, tid, qid).
Pharmaceutical additives: Coloring, flavoring and sweetening agents, co-solvents, preservatives and
their applications.
Unit III
Pharmaceutical calculations: Weights and measures, weighing of solids and measurement of liquids.
Posology: Introduction, calculation of doses for infants, enlarging and reducing recipes.
Percentage solutions, alligation method, alcohol dilution, proof spirit.
Unit IV
Introduction to Pharmaceutical dosage forms: Classification, formulation methods of powders,
mixtures, syrups and elixirs and their labeling requirements.
Definitions: Solutions, spirits, infusions, paints, aromatic waters, mouth washes, gargles, lotions,
liniments, pastes, ointments, creams, inhalations, tinctures, lozenges and pastilles.
Unit V
Size Reduction: Definition, principles, laws and mechanisms governing size reduction, factors affecting
size reduction. Study of ball mill and fluid energy mill. Introduction to sieving methods.
Mixing: Theory of mixing, solid-solid, solid-liquid and liquid-liquid mixing equipments.
RPH-102P/RPH-202P
PHARMACEUTICS-I (GENERAL PHARMACY)
PRACTICAL
1. Preparation of following classes of pharmaceutical dosage forms (involving the
use of calculations in metrology) as official in I.P., B.P., U.S.P-N.F.
a) Aromatic Waters i. Chloroform Water B.P.
ii. Concentrated Peppermint Water B.P.
iii. Strong Rose Water U.S.P.-N.F.
b) Mixtures i. Mixture of Precipitated Chalk B.P.
ii. Kaolin Mixture B.P.
c) Syrups i. Simple Syrup B.P./U.S.P./I.P.
ii. Ferrous Sulphate Syrup U.S.P.
d) Powders i. ORS Powder I.P.
ii. Absorbable Dusting Powder U.S.P.-N.F.
iii. Effervescent Compound Powder B.P.C.
2. Study of the role of pharmaceutical additives in formulations
a) Colouring agent: i. Compound Sodium Chloride Mouthwash B.P.
ii. Phenol Gargle B.P.C.
b) Flavouring agent: i. Orange Tincture I.P.
ii. Potassium Citrate Mixture B.P.
c) Sweetening agents: i. Simple Elixir I.P.
d) Cosolvents: i. Camphor Water I.P.
ii. Compound Iodine Throat Paint I.P. (Mandl’s Paint)
e) Preservatives: i. Compound Zinc Sulphate Mouthwash B.P.C.
ii. Calamine Lotion I.P.
f) Surfactants: i. Cresol with Soap Solution I.P.
ii. Turpentine Liniment B.P.
3. Experiments to illustrate principles of size reduction using Ball Mill. Effect of size of balls,
number of balls and time on the efficiency of ball mill.
4. Experiments to illustrate mixing efficiency.
BOOKS RECOMMENDED:
1. Pharmacopoeia of India, The Controller of Publications, Delhi.
2. British Pharmacopoeia, Her Majesty’s Stationary Office, University Press, Cambridge.
3. United States Pharmacopoeia (National Formulary).
4. Carter S.J., “Cooper and Gunn’s Tutorial Pharmacy, CBS Publishers, Delhi.
5. Rawlins E.A., Bentley’s Text Book of Pharmaceutics, ELBS Bailliere Tindall.
6. Lachman L, Lieberman H.A and Kanig J.L., Theory and Practice of Industrial Pharmacy, Lea
& Febiger, Philadelphia.
7. Cooper and Gunn’s Dispensing for Pharmaceutical Students, CBS Publishers, New Delhi.
8. Aulton M.E, Text Book of Pharmaceutics, Vol., I & II. Churchill Livingstone, London.
9. Remington, The Science and Practice of Pharmacy Vol. I & II. Mack Publishing Co.,
Pennsylvania.
10. Jain N.K., Modern Dispensing Pharmacy, 2nd Ed, PharmaMed Press/BPS Books,
Hyderabad.
RPH-103
ANATOMY, PHYSIOLOGY AND PATHOPHYSIOLOGY- I
Unit I
Introduction to human body and organization of human body.
Functional and structural characteristics of cell.
Structural and functional characteristics of tissues- epithelial, connective, muscle and nerve.
Unit II
Skeletal system: Structure, composition and functions of skeleton. Classification of joints, types of
movements of joints.
Muscular system: Anatomy and physiology of skeletal and smooth muscle, energy metabolism, types
of muscle contraction, muscle tone.
Unit III
Sense organs: Basic anatomy and physiology of the eye (vision), ear (hearing), taste buds, nose (smell),
and skin (superficial receptors).
Unit IV
Communicable diseases: Brief outline, causative agents, modes of transmission and prevention
(chicken pox, measles, influenza, diphtheria, tetanus, tuberculosis, leprosy, poliomyelities, malaria,
rabies, dengue).
Unit V
Demography and family planning, medical termination of pregnancy.
First aid: Emergency treatment of shock, snake bites, burns, poisoning, fractures and resuscitation
methods
RPH-103P
ANATOMY, PHYSIOLOGY AND PATHOPHYSIOLOGY-I
PRACTICAL
1. Study of types of microscopes, their parts and functions.
2. To draw and study the organization of human body.
3. To study the human skeletal system.
4. To study various types of joints.
5. To study different prepared slides- such as muscle, nerve cells, epithelial tissues, connective tissues
etc.
6. Examination of color vision and acuity of vision.
7. Identification of different tastes.
8. Examination of ear.
9. Techniques of tying of different types of bandages.
10. Study of emergency treatments in case of burns and poisoning.
11. To prepare and study different charts related to pathophysiology of communicable diseases.
BOOKS RECOMMENDED:
1. Marieb E.N. Human Anatomy and Physiology, Benzamin Cummings (Pearson Education Inc.), San
Francisco.
2. Park K., Preventive and Social Medicine, Banarsidas Bhanot Publishers, Jabalpur.
3. Seeley R.R., Stephens T.D. and Tate P. Essentials of Anatomy and Physiology, McGraw-Hill, New
York.
4. Tortora G.J, and Anagnodokos NP Principles of Anatomy and Physiology, Harper & Row
Publishers, New Delhi.
5. Ross & Wilson Anatomy and Physiology in Health and Illness, Churchill Livingstone, London.
6. Chatterjee C.C. Human Physiology, Medical Allied Agency, Calcutta.
7. Parmar N.S. Health Education and Community Pharmacy, CBS Publishers, Delhi.
8. Keele, C.A., Niel, E and Joels N, Samson Wright’s Applied Physiology, Oxford University Press,
New York.
9. Dandiya, P.C., Zafer, Z.Y.K., and Zafer, A. Health Education and Community Pharmacy, Vallabh
Prakashan, Delhi.
RPH-104/RPH204
PHARMACEUTICAL ANALYSIS-I
Unit I
Fundamentals of volumetric analysis, preliminaries and definitions, precision and accuracy, types of
errors, methods of expressing concentration, primary and secondary standards, different techniques of
analysis, Factors affecting the choice of analytical methods, significance of quantitative analysis in
quality control.
Unit II
Acid base titrations: Acid base concepts, role of solvent, relative strengths of acids and bases,
ionization, common-ion effect, pH, hydrolysis of salts, Henderson-Hasselbach equation, buffer solution,
neutralization curves, acid base indicators, theory of indicators, choice of indicators, mixed indicators,
polyprotic system. Assay of boric acid as per I.P.
Unit III
Oxidation reduction titrations: Concepts of oxidation and reduction, equivalent weights of oxidizing
and reducing agents, theory of redox titrations-redox indicators, oxidation reduction curves. Titrations
involving ceric sulphate, potassium permanganate, iodimetry and iodometry. Assay of ascorbic acid
tablet as per I.P.
Unit IV
Complexometric titrations: Principle, complexing agents, indicators, masking and demasking, types
of complexometric titrations and applications. Assay of alum and determination of hardness of water.
Precipitation titrations: Precipitation reactions and techniques, solubility products, Mohr’s method,
Volhard’s method and Fajan’s method.
Unit V
Miscellaneous methods of analysis: Diazotization titrations, Karl-Fischer titration. Kjeldahl’s method
of nitrogen determination. Radioassays (Autoradiography, RIA). Assay of sodium iodide (131I) solution
as per I.P.
RPH-104P/RPH-204
PHARMACEUTICAL ANALYSIS-I
PRACTICAL
1. Study of general glassware and apparatus required for various analytical procedures.
2. Study of various types of balances, standardization of analytical weights, weighing and calibration of
volumetric apparatus.
3. Preparation and standardization of acids and bases (Primary and secondary standards) as per I.P.
4. Assay procedure of various drugs using acid base titrations as per I.P.
5. Preparation and standardization of some redox titrants (potassium permanganate, potassium
dichromate, iodine, sodium thiosulphate etc).
6. Assay procedure of various drugs using redox titrations as per I.P.
7. Preparation and standardization of EDTA as per I.P.
8. Assay of magnesium hydroxide and magnesium sulfate as per I.P.
9. Determination of hardness of water as per I.P.
10. Preparation and standardization of sodium nitrite as per I.P.
11. Assay of sulfa drugs using diazotization titration as per I.P.
12. Estimation of nitrogen in some organic compounds using Kjeldahl method.
13. Preparation and standardization of silver nitrate and ammonium thiocyanate as per I.P.
14. Titrations based on Mohr’s, Volhard's and Fajan’s methods.
BOOKS RECOMMENDED:
1. Mendhanm J., Denny R.C., Barnes J.D., Thomas M, Jeffery G.H., Vogel’s Textbook of Quantitative
Chemical Analysis, Pearson Education Asia.
2. Conners K.A., A Text book of Pharmaceutical Analysis, Wiley Inter-science.
3. Beckett A.H., and Stenlake J.B., Practical Pharmaceutical Chemistry, Vol. I & II. Athlone Press,
University of London.
4. British Pharmacopoeia, Her Majesty’s Stationary Office, University Press, Cambridge.
5. Alexeyev V. Quantitative Analysis. CBS Publishers & Distributors, New Delhi.
6. The Pharmacopoeia of India, The Controller of Publications, Delhi.
RPH-105/RPH-205
COMPUTER FUNDAMENTALS
Unit I
Definition and overview of computer, computer classification, computer organization, computer
code, input devices, output devices, storage devices. Computer software, types of software.
overview of computer networks, LAN, MAN, WAN. Internet, network topology. Internetworking:
Bridges, repeaters and routers.
Unit II
Introduction: Operating system and function, evolution of operating system, batch, interactive,
time sharing and real time system. Single user operating system and multi-user operating system.
Basics in MS-DOS, internal and external commands in MS-DOS.
Unit III
Introduction to MS-OFFICE-2007, word 2007 document creation, editing, formatting table
handling, mail merge. Excel-2007, editing, working retrieval, important functions, short cut keys
used in EXCEL.
Unit IV
MS-Power point 2007-Job Profile, elements of Power point , ways of delivering presentation,
concept of Four P’s (planning, preparation, practice and presentation) ways of handling
presentations, e.g. creating, saving slides show controls, adding formatting, animation and
multimedia effects.
Unit V
Computer applications in pharmaceutical and clinical studies, uses of internet in pharmaceutical
industry.
RPH-105/RPH-205
COMPUTER FUNDAMENTALS
PRACTICAL
Software lab to be used for the following:-
1. Windows, Managing Windows, Working with Disk, Folders and files.
2. MS-Office 2003 (MS Word, MS Power point, MS Excel, MS Access).
3. Computer Operating System like DOS and Windows.
4. Internet Features (E-mail, Browser etc.).
BOOKS RECOMMENDED
1. Sinha R.K., Computer Fundamentals, BPB Publications, New Delhi.
2. Raja Raman V., Computer Programming in ‘C’, PHI Publication, New Delhi.
3. Hunt N and Shelley J., Computers and Common Sense, Prentice Hall of India, New Delhi.
4. Tiwari, N.K., Computer fundamentals with Pharmacy Applications, PharmaMed Press, Hyderabad.
5. Rao G.N., Biostatistics and Computer Applications, PharmaMed Press/ BSP Books, Hyderabad.
6. Mansfield R., Working in Microsoft Office, Tata McGraw-Hill Publishing Company Ltd, New
Delhi.
7. Leon M. and Leon A., Fundamentals of Computer Science and Communication Engineering",
UBS Publishers Distributors Ltd, New Delhi.
8. Norton, P. Peter Norton's Introduction to Computers, Tata McGraw-Hill, New Delhi.
Scheme of Evaluation (Choice Based Credit System) Bachelor of Pharmacy (B. Pharm.) FIRST SEMESTER
 |
| B PHARMA PHARMACY 1ST SEMESTER EVALUATION SCHEME |
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